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Cytokine production capabilities of human primary monocyte-derived macrophages from patients with diabetes mellitus type 2 with and without diabetic peripheral neuropathy

INTRODUCTION: Monocytes from patients with diabetes mellitus type 2 (DM2) are dysfunctional, persistently primed, and prone to a proinflammatory phenotype. This may alter the phenotype of their differentiation to macrophages and result in diabetic peripheral neuropathy (DPN), nerve damage, nerve sen...

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Detalles Bibliográficos
Autores principales: Alvarado-Vázquez, Perla Abigail, Grosick, Rachel L, Moracho-Vilrriales, Carolina, Ward, Eileen, Threatt, Tiffaney, Romero-Sandoval, Edgar Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305162/
https://www.ncbi.nlm.nih.gov/pubmed/30588081
http://dx.doi.org/10.2147/JPR.S186372