Cargando…

G(i/o) protein-coupled receptors in dopamine neurons inhibit the sodium leak channel NALCN

Dopamine (D2) receptors provide autoinhibitory feedback onto dopamine neurons through well-known interactions with voltage-gated calcium channels and G protein-coupled inwardly-rectifying potassium (GIRK) channels. Here, we reveal a third major effector involved in D2R modulation of dopaminergic neu...

Descripción completa

Detalles Bibliográficos
Autores principales: Philippart, Fabian, Khaliq, Zayd M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305199/
https://www.ncbi.nlm.nih.gov/pubmed/30556810
http://dx.doi.org/10.7554/eLife.40984