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Genetic analysis reveals functions of atypical polyubiquitin chains

Although polyubiquitin chains linked through all lysines of ubiquitin exist, specific functions are well-established only for lysine-48 and lysine-63 linkages in Saccharomyces cerevisiae. To uncover pathways regulated by distinct linkages, genetic interactions between a gene deletion library and a p...

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Detalles Bibliográficos
Autores principales: Meza Gutierrez, Fernando, Simsek, Deniz, Mizrak, Arda, Deutschbauer, Adam, Braberg, Hannes, Johnson, Jeffrey, Xu, Jiewei, Shales, Michael, Nguyen, Michelle, Tamse-Kuehn, Raquel, Palm, Curt, Steinmetz, Lars M, Krogan, Nevan J, Toczyski, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305200/
https://www.ncbi.nlm.nih.gov/pubmed/30547882
http://dx.doi.org/10.7554/eLife.42955