Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion

Erythrocyte Binding Antigen of 175 kDa (EBA-175) has a well-defined role in binding to glycophorin A (GpA) during Plasmodium falciparum invasion of erythrocytes. However, EBA-175 is shed post invasion and a role for this shed protein has not been defined. We show that EBA-175 shed from parasites pro...

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Detalles Bibliográficos
Autores principales: Paing, May M, Salinas, Nichole D, Adams, Yvonne, Oksman, Anna, Jensen, Anja TR, Goldberg, Daniel E, Tolia, Niraj H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305201/
https://www.ncbi.nlm.nih.gov/pubmed/30556808
http://dx.doi.org/10.7554/eLife.43224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305201/
https://www.ncbi.nlm.nih.gov/pubmed/30556808
http://dx.doi.org/10.7554/eLife.43224

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