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False positives in trans-eQTL and co-expression analyses arising from RNA-sequencing alignment errors
Sequence similarity among distinct genomic regions can lead to errors in alignment of short reads from next-generation sequencing. While this is well known, the downstream consequences of misalignment have not been fully characterized. We assessed the potential for incorrect alignment of RNA-sequen...
Autores principales: | Saha, Ashis, Battle, Alexis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305209/ https://www.ncbi.nlm.nih.gov/pubmed/30613398 http://dx.doi.org/10.12688/f1000research.17145.2 |
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