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Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD (+) depletion
Background: Skeletal muscle is central to whole body metabolic homeostasis, with age and disease impairing its ability to function appropriately to maintain health. Inadequate NAD (+) availability is proposed to contribute to pathophysiology by impairing metabolic energy pathway use. Despite the imp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305244/ https://www.ncbi.nlm.nih.gov/pubmed/30607371 http://dx.doi.org/10.12688/wellcomeopenres.14898.2 |