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Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD (+) depletion

Background: Skeletal muscle is central to whole body metabolic homeostasis, with age and disease impairing its ability to function appropriately to maintain health. Inadequate NAD (+) availability is proposed to contribute to pathophysiology by impairing metabolic energy pathway use. Despite the imp...

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Detalles Bibliográficos
Autores principales: Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian, Lavery, Gareth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305244/
https://www.ncbi.nlm.nih.gov/pubmed/30607371
http://dx.doi.org/10.12688/wellcomeopenres.14898.2

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