Cargando…
Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD (+) depletion
Background: Skeletal muscle is central to whole body metabolic homeostasis, with age and disease impairing its ability to function appropriately to maintain health. Inadequate NAD (+) availability is proposed to contribute to pathophysiology by impairing metabolic energy pathway use. Despite the imp...
Autores principales: | Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian, Lavery, Gareth G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305244/ https://www.ncbi.nlm.nih.gov/pubmed/30607371 http://dx.doi.org/10.12688/wellcomeopenres.14898.2 |
Ejemplares similares
-
OR03-06 NAD+ Availability Modulates 11β-HSD1-Mediated Glucocorticoid Regeneration in Mouse Skeletal Muscle
por: Elhassan, Yasir S, et al.
Publicado: (2020) -
SUN-103 A Direct Comparison Of Metabolic Responses To Nad Repletion In C57bl/6j And C57bl/6n Diet-induced Obesity Mouse Models
por: Garten, Andrea Antje, et al.
Publicado: (2019) -
Induction of the nicotinamide riboside kinase NAD(+) salvage pathway in a model of sarcoplasmic reticulum dysfunction
por: Doig, Craig L., et al.
Publicado: (2020) -
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
por: Elhassan, Yasir S., et al.
Publicado: (2019) -
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
por: Fletcher, Rachel S., et al.
Publicado: (2017)