Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease

Polymorphic alleles in the apolipoprotein E (APOE) gene are the main genetic determinants of late-onset Alzheimer's disease (AD) risk. Individuals carrying the APOE E4 allele are at increased risk to develop AD compared to those carrying the more common E3 allele, whereas those carrying the E2...

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Detalles Bibliográficos
Autores principales: Dai, Jingting, Johnson, Erik C. B., Dammer, Eric B., Duong, Duc M., Gearing, Marla, Lah, James J., Levey, Allan I., Wingo, Thomas S., Seyfried, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305300/
https://www.ncbi.nlm.nih.gov/pubmed/30618606
http://dx.doi.org/10.3389/fnmol.2018.00454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305300/
https://www.ncbi.nlm.nih.gov/pubmed/30618606
http://dx.doi.org/10.3389/fnmol.2018.00454

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