Mesenteric CD103(+)DCs Initiate Switched Coxsackievirus B3 VP1-Specific IgA Response to Intranasal Chitosan-DNA Vaccine Through Secreting BAFF/IL-6 and Promoting Th17/Tfh Differentiation

Intranasal chitosan-formulated DNA vaccination promotes IgA secretion in the intestine. However, the mechanism whereby chitosan-DNA skews IgA class switch recombination (CSR) of B cells in the Gut-associated lymph tissue (GALT) is not fully resolved. In this study, we investigated the effects of nas...

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Detalles Bibliográficos
Autores principales: Zhao, Haoxin, Yang, Jie, Qian, Qian, Wu, Manli, Li, Min, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305319/
https://www.ncbi.nlm.nih.gov/pubmed/30619341
http://dx.doi.org/10.3389/fimmu.2018.02986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305319/
https://www.ncbi.nlm.nih.gov/pubmed/30619341
http://dx.doi.org/10.3389/fimmu.2018.02986

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