Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients

The purpose of this study was to identify genotypes associated with dose-adjusted tacrolimus trough concentrations (C(0)/D) in kidney transplant recipients using whole-exome sequencing (WES). This study included 147 patients administered tacrolimus, including seventy-five patients in the discovery s...

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Detalles Bibliográficos
Autores principales: Sohn, Minji, Kim, Myeong Gyu, Han, Nayoung, Kim, In-Wha, Gim, Jungsoo, Min, Sang-Il, Song, Eun Young, Kim, Yon Su, Jung, Hun Soon, Shin, Young Kee, Ha, Jongwon, Oh, Jung Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305386/
https://www.ncbi.nlm.nih.gov/pubmed/30584253
http://dx.doi.org/10.1038/s41598-018-36085-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305386/
https://www.ncbi.nlm.nih.gov/pubmed/30584253
http://dx.doi.org/10.1038/s41598-018-36085-w

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