Dendrobium nobile Lindl. Alkaloids Decreases the Level of Intracellular β-Amyloid by Improving Impaired Autolysosomal Proteolysis in APP/PS1 Mice

As the major degradation pathway for long-lived proteins and organelles, macroautophagy is a decisive factor for the survival and longevity of cells. The existing evidence indicates that the disruption of substrate proteolysis in autolysosomes is the main mechanism underlying autophagy failure in Al...

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Detalles Bibliográficos
Autores principales: Nie, Jing, Jiang, Lin-Shan, Zhang, Yu, Tian, Yong, Li, Li-Sheng, Lu, Yan-Liu, Yang, Wen-Jin, Shi, Jing-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305391/
https://www.ncbi.nlm.nih.gov/pubmed/30618767
http://dx.doi.org/10.3389/fphar.2018.01479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305391/
https://www.ncbi.nlm.nih.gov/pubmed/30618767
http://dx.doi.org/10.3389/fphar.2018.01479

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