Cargando…

Listeria monocytogenes Relies on the Heme-Regulated Transporter hrtAB to Resist Heme Toxicity and Uses Heme as a Signal to Induce Transcription of lmo1634, Encoding Listeria Adhesion Protein

For pathogenic bacteria, host-derived heme represents an important metabolic cofactor and a source for iron. However, high levels of heme are toxic to bacteria. We have previously shown that excess heme has a growth-inhibitory effect on the Gram-positive foodborne pathogen Listeria monocytogenes, an...

Descripción completa

Detalles Bibliográficos
Autores principales: dos Santos, Patrícia Teixeira, Larsen, Pernille Tholund, Menendez-Gil, Pilar, Lillebæk, Eva Maria Sternkopf, Kallipolitis, Birgitte Haahr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305404/
https://www.ncbi.nlm.nih.gov/pubmed/30619169
http://dx.doi.org/10.3389/fmicb.2018.03090