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Listeria monocytogenes Relies on the Heme-Regulated Transporter hrtAB to Resist Heme Toxicity and Uses Heme as a Signal to Induce Transcription of lmo1634, Encoding Listeria Adhesion Protein
For pathogenic bacteria, host-derived heme represents an important metabolic cofactor and a source for iron. However, high levels of heme are toxic to bacteria. We have previously shown that excess heme has a growth-inhibitory effect on the Gram-positive foodborne pathogen Listeria monocytogenes, an...
Autores principales: | dos Santos, Patrícia Teixeira, Larsen, Pernille Tholund, Menendez-Gil, Pilar, Lillebæk, Eva Maria Sternkopf, Kallipolitis, Birgitte Haahr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305404/ https://www.ncbi.nlm.nih.gov/pubmed/30619169 http://dx.doi.org/10.3389/fmicb.2018.03090 |
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