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CD6, a Rheostat-Type Signalosome That Tunes T Cell Activation

Following T cell receptor triggering, T cell activation is initiated and amplified by the assembly at the TCR/CD3 macrocomplex of a multitude of stimulatory enzymes that activate several signaling cascades. The potency of signaling is, however, modulated by various inhibitory components already at t...

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Detalles Bibliográficos
Autores principales: Gonçalves, Carine M., Henriques, Sónia N., Santos, Rita F., Carmo, Alexandre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305463/
https://www.ncbi.nlm.nih.gov/pubmed/30619347
http://dx.doi.org/10.3389/fimmu.2018.02994