Cargando…
CD6, a Rheostat-Type Signalosome That Tunes T Cell Activation
Following T cell receptor triggering, T cell activation is initiated and amplified by the assembly at the TCR/CD3 macrocomplex of a multitude of stimulatory enzymes that activate several signaling cascades. The potency of signaling is, however, modulated by various inhibitory components already at t...
Autores principales: | Gonçalves, Carine M., Henriques, Sónia N., Santos, Rita F., Carmo, Alexandre M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305463/ https://www.ncbi.nlm.nih.gov/pubmed/30619347 http://dx.doi.org/10.3389/fimmu.2018.02994 |
Ejemplares similares
-
Tuning the rheostat of immune gene translation
por: Huang, Shuai
Publicado: (2023) -
CD6-mediated inhibition of T cell activation via modulation of Ras
por: Henriques, Sónia N., et al.
Publicado: (2022) -
CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs
por: Zapata, Juan M., et al.
Publicado: (2018) -
The Murine CD137/CD137 Ligand Signalosome: A Signal Platform Generating Signal Complexity
por: Choi, Beom K., et al.
Publicado: (2020) -
Structural Evolution of TIR-Domain Signalosomes
por: Nimma, Surekha, et al.
Publicado: (2021)