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High Levels of Eomes Promote Exhaustion of Anti-tumor CD8(+) T Cells
Eomes, a T-box transcription factor, is known important for both function and homeostasis of effector and memory T cells, but was recently also implicated in CD8(+) T cell exhaustion. However, whether and how Eomes might regulate effector functions or exhaustion of CD8(+) T cells, especially in the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305494/ https://www.ncbi.nlm.nih.gov/pubmed/30619337 http://dx.doi.org/10.3389/fimmu.2018.02981 |