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Arrestin-mediated signaling: Is there a controversy?

The activation of the mitogen-activated protein (MAP) kinases extracellular signal-regulated kinase (ERK)1/2 was traditionally used as a readout of signaling of G protein-coupled receptors (GPCRs) via arrestins, as opposed to conventional GPCR signaling via G proteins. Several recent studies using H...

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Detalles Bibliográficos
Autores principales: Gurevich, Vsevolod V, Gurevich, Eugenia V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305498/
https://www.ncbi.nlm.nih.gov/pubmed/30595812
http://dx.doi.org/10.4331/wjbc.v9.i3.25