Activation of the Large-Conductance, Voltage, and Ca(2+)- Activated K(+) (BK) Channel in Acute Spinal Cord Injury in the Wistar Rat Is Neuroprotective

Context/Objectives: Spinal cord injury (SCI) results in significant neuronal and glial cell death resulting in impaired neurological and motor function. Uncontrolled Ca(2+) entry results in excitotoxicity and cell death. In this study, we examine the use of a BK channel activator, Isopimaric acid (I...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacobsen, Marianne, Lett, Kristen, Barden, John Mark, Simpson, Gavin L., Buttigieg, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305522/
https://www.ncbi.nlm.nih.gov/pubmed/30619063
http://dx.doi.org/10.3389/fneur.2018.01107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305522/
https://www.ncbi.nlm.nih.gov/pubmed/30619063
http://dx.doi.org/10.3389/fneur.2018.01107

Ejemplares similares