Cargando…

Activation of the Large-Conductance, Voltage, and Ca(2+)- Activated K(+) (BK) Channel in Acute Spinal Cord Injury in the Wistar Rat Is Neuroprotective

Context/Objectives: Spinal cord injury (SCI) results in significant neuronal and glial cell death resulting in impaired neurological and motor function. Uncontrolled Ca(2+) entry results in excitotoxicity and cell death. In this study, we examine the use of a BK channel activator, Isopimaric acid (I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jacobsen, Marianne, Lett, Kristen, Barden, John Mark, Simpson, Gavin L., Buttigieg, Josef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305522/ https://www.ncbi.nlm.nih.gov/pubmed/30619063 http://dx.doi.org/10.3389/fneur.2018.01107

Ejemplares similares

Mechanism of voltage sensing in Ca(2+)- and voltage-activated K(+) (BK) channels
por: Carrasquel-Ursulaez, Willy, et al.
Publicado: (2022)

Coupling between Voltage Sensor Activation, Ca(2+) Binding and Channel Opening in Large Conductance (BK) Potassium Channels
por: Horrigan, Frank T., et al.
Publicado: (2002)

Hypoxic Regulation of the Large-Conductance, Calcium and Voltage-Activated Potassium Channel, BK
por: Ochoa, Sara V., et al.
Publicado: (2021)

Cysteine Modification Alters Voltage- and Ca(2+)-dependent Gating of Large Conductance (BK) Potassium Channels
por: Zhang, Guangping, et al.
Publicado: (2005)

An Electrostatic Switch Controls Palmitoylation of the Large Conductance Voltage- and Calcium-activated Potassium (BK) Channel
por: Jeffries, Owen, et al.
Publicado: (2012)

Correction for Carrasquel-Ursulaez et al., Mechanism of voltage sensing in Ca2(+)- and voltage-activated K(+) (BK) channels
Publicado: (2022)

Proximal clustering between BK and Ca(V)1.3 channels promotes functional coupling and BK channel activation at low voltage
por: Vivas, Oscar, et al.
Publicado: (2017)

Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca(2+)
por: Shelley, Christopher, et al.
Publicado: (2010)

Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca(2+)-Activated K(+) Channels (BK(Ca))
por: Tseng, Hisa Hui Ling, et al.
Publicado: (2016)

Positions of β2 and β3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel
por: Wu, Roland S., et al.
Publicado: (2013)

Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channel
por: Pantazis, Antonios, et al.
Publicado: (2010)

Measurements of the BK(Ca) Channel's High-Affinity Ca(2+) Binding Constants: Effects of Membrane Voltage
por: Sweet, Tara-Beth, et al.
Publicado: (2008)

S-acylation dependent post-translational cross-talk regulates large conductance calcium- and voltage- activated potassium (BK) channels
por: Shipston, Michael J.
Publicado: (2014)

Ca(2+)- and Voltage-Activated K(+) (BK) Channels in the Nervous System: One Gene, a Myriad of Physiological Functions
por: Ancatén-González, Carlos, et al.
Publicado: (2023)

Natural Bile Acids and Synthetic Analogues Modulate Large Conductance Ca(2+)-activated K(+) (BK(Ca)) Channel Activity in Smooth Muscle Cells
por: Dopico, Alejandro M., et al.
Publicado: (2002)

Electromagnetic energy (670 nm) stimulates vasodilation through activation of the large conductance potassium channel (BK(Ca))
por: Gebremendhin, Debebe, et al.
Publicado: (2021)

Voltage-dependent Ca(2+) channels, not ryanodine receptors, activate Ca(2+)-dependent BK potassium channels in human retinal pigment epithelial cells
por: Wimmers, Sönke, et al.
Publicado: (2008)

Intrinsic Voltage Dependence and Ca(2+) Regulation of mslo Large Conductance Ca-activated K(+) Channels
por: Cui, J., et al.
Publicado: (1997)

Intra- and Intersubunit Cooperativity in Activation of BK Channels by Ca(2+)
por: Qian, Xiang, et al.
Publicado: (2006)

Measuring the Influence of the BK(Ca) β1 Subunit on Ca(2+) Binding to the BK(Ca) Channel
por: Sweet, Tara-Beth, et al.
Publicado: (2009)

The molecular nature of the 17β-Estradiol binding site in the voltage- and Ca(2+)-activated K(+) (BK) channel β1 subunit
por: Granados, Sara T., et al.
Publicado: (2019)

Mitochondrial BK(Ca) channel
por: Balderas, Enrique, et al.
Publicado: (2015)

Overexpression of the Large-Conductance, Ca(2+)-Activated K(+) (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes
por: Stimers, Joseph R., et al.
Publicado: (2015)

Stimulatory Role of SPAK Signaling in the Regulation of Large Conductance Ca(2+)-Activated Potassium (BK) Channel Protein Expression in Kidney
por: Bi, Ye, et al.
Publicado: (2020)

Coupling of voltage-dependent gating and Ba++ block in the high- conductance, Ca++-activated K+ channel
Publicado: (1987)

BK(Ca) Channels as Targets for Cardioprotection
por: Szteyn, Kalina, et al.
Publicado: (2020)

Large Conductance Ca(2+)-Activated K(+) Channel (BK(Ca)) α-Subunit Splice Variants in Resistance Arteries from Rat Cerebral and Skeletal Muscle Vasculature
por: Nourian, Zahra, et al.
Publicado: (2014)

Functional insights into modulation of BK(Ca) channel activity to alter myometrial contractility
por: Lorca, Ramón A., et al.
Publicado: (2014)

Luteolin-Induced Activation of Mitochondrial BK(Ca) Channels: Undisclosed Mechanism of Cytoprotection
por: Kampa, Rafał P., et al.
Publicado: (2022)

RIM‐binding proteins recruit BK‐channels to presynaptic release sites adjacent to voltage‐gated Ca(2+)‐channels
por: Sclip, Alessandra, et al.
Publicado: (2018)

Effect of Phosphatidylserine on Unitary Conductance and Ba(2+) Block of the BK Ca(2+)–activated K(+) Channel: Re-examination of the Surface Charge Hypothesis
por: Park, Jin Bong, et al.
Publicado: (2003)

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I(bk,Ca))
por: Horváth, András, et al.
Publicado: (2020)

Voltage and Ca(2+) Activation of Single Large-Conductance Ca(2+)-Activated K(+) Channels Described by a Two-Tiered Allosteric Gating Mechanism
por: Rothberg, Brad S., et al.
Publicado: (2000)

Calcium-driven regulation of voltage-sensing domains in BK channels
por: Lorenzo-Ceballos, Yenisleidy, et al.
Publicado: (2019)

The Large Conductance, Calcium-activated K(+) (BK) Channel is regulated by Cysteine String Protein
por: Kyle, Barry D., et al.
Publicado: (2013)

Contributions of Ca(V)1.3 Channels to Ca(2+) Current and Ca(2+)-Activated BK Current in the Suprachiasmatic Nucleus
por: McNally, Beth A., et al.
Publicado: (2021)

BK(Ca) channel dysfunction in neurological diseases
por: N'Gouemo, Prosper
Publicado: (2014)

Regulatory mechanisms of mitochondrial BK(Ca) channels
por: González-Cota, Ana L., et al.
Publicado: (2021)

Large conductance Ca(2+)‐activated K(+) (BK) channels promote secretagogue‐induced transition from spiking to bursting in murine anterior pituitary corticotrophs
por: Duncan, Peter J., et al.
Publicado: (2015)

Assessment of the Neuroprotective Effects of Lavandula angustifolia Extract on the Contusive Model of Spinal Cord Injury in Wistar Rats
por: Kaka, Gholamreza, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_80vkpsffcrqg3nesa2b16utrrt