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Genetic Variants Associated With Neurodegenerative Diseases Regulate Gene Expression in Immune Cell CD14+ Monocytes

Until now, large-scale genome-wide association studies have identified 94 genes associated with Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Expression quantitative trait locus (eQTL) analysis showed that six genetic variants around six of these 94 genes could drive bo...

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Detalles Bibliográficos
Autores principales: Sun, Jing-yi, Hou, Ya-jun, Zhang, Yan, Wang, Longcai, Liu, Lidong, Sun, Bao-liang, Yuan, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305550/
https://www.ncbi.nlm.nih.gov/pubmed/30619483
http://dx.doi.org/10.3389/fgene.2018.00666