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Kaposi’s Sarcoma-Associated Herpesvirus-Encoded Viral IL-6 (vIL-6) Enhances Immunoglobulin Class-Switch Recombination

Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic gamma-herpesvirus that causes AIDS-associated Kaposi sarcoma (KS) and several lymphoproliferative disorders. During the humoral immune response antigen-activated mature B cells acquire functional diversification by immunoglobulin heavy c...

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Detalles Bibliográficos
Autores principales: Rosario, Santas A., Santiago, Gabriel E., Mesri, Enrique A., Verdun, Ramiro E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305588/
https://www.ncbi.nlm.nih.gov/pubmed/30619193
http://dx.doi.org/10.3389/fmicb.2018.03119