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Signal Transduction in Human Cell Lysate via Dynamic RNA Nanotechnology

[Image: see text] Dynamic RNA nanotechnology with small conditional RNAs (scRNAs) offers a promising conceptual approach to introducing synthetic regulatory links into endogenous biological circuits. Here, we use human cell lysate containing functional Dicer and RNases as a testbed for engineering s...

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Detalles Bibliográficos
Autores principales: Hochrein, Lisa M., Ge, Tianjia J., Schwarzkopf, Maayan, Pierce, Niles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305621/
https://www.ncbi.nlm.nih.gov/pubmed/30525469
http://dx.doi.org/10.1021/acssynbio.8b00424