Recruitment of Antigen Presenting Cells to Skin Draining Lymph Node From HPV16E7-Expressing Skin Requires E7-Rb Interaction

“High-risk” human papillomaviruses (HPV) infect keratinocytes of squamous epithelia. The HPV16E7 protein induces epithelial hyperplasia by binding Rb family proteins and disrupting cell cycle termination. Murine skin expressing HPV16E7 as a transgene from a keratin 14 promoter (K14.E7) demonstrates...

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Detalles Bibliográficos
Autores principales: Kuo, Paula, Teoh, Siok Min, Tuong, Zewen K., Leggatt, Graham R., Mattarollo, Stephen R., Frazer, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305623/
https://www.ncbi.nlm.nih.gov/pubmed/30619266
http://dx.doi.org/10.3389/fimmu.2018.02896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305623/
https://www.ncbi.nlm.nih.gov/pubmed/30619266
http://dx.doi.org/10.3389/fimmu.2018.02896

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