Mitochondrial and nuclear disease panel (Mito‐aND‐Panel): Combined sequencing of mitochondrial and nuclear DNA by a cost‐effective and sensitive NGS‐based method

BACKGROUND: The diagnosis of mitochondrial disorders is challenging because of the clinical variability and genetic heterogeneity of these conditions. Next‐Generation Sequencing (NGS) technology offers a robust high‐throughput platform for nuclear and mitochondrial DNA (mtDNA) analyses. METHOD: We d...

Descripción completa

Detalles Bibliográficos
Autores principales: Abicht, Angela, Scharf, Florentine, Kleinle, Stephanie, Schön, Ulrike, Holinski‐Feder, Elke, Horvath, Rita, Benet‐Pagès, Anna, Diebold, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305657/
https://www.ncbi.nlm.nih.gov/pubmed/30406974
http://dx.doi.org/10.1002/mgg3.500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305657/
https://www.ncbi.nlm.nih.gov/pubmed/30406974
http://dx.doi.org/10.1002/mgg3.500

Ejemplares similares