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Mu-Opioid Receptor Agonist Induces Kir3 Currents in Mouse Peripheral Sensory Neurons – Effects of Nerve Injury

Neuropathic pain often arises from damage to peripheral nerves and is difficult to treat. Activation of opioid receptors in peripheral sensory neurons is devoid of respiratory depression, sedation, nausea, and addiction mediated in the brain, and ameliorates neuropathic pain in animal models. Mechan...

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Detalles Bibliográficos
Autores principales: Stötzner, Philip, Spahn, Viola, Celik, Melih Ö., Labuz, Dominika, Machelska, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305728/
https://www.ncbi.nlm.nih.gov/pubmed/30618766
http://dx.doi.org/10.3389/fphar.2018.01478