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Design and Validation of a Multiplex KIR and HLA Class I Genotyping Method Using Next Generation Sequencing

Killer cell immunoglobulin-like receptors (KIR), considered the most polymorphic natural killer (NK) cell regulators, bind HLA class-I molecules or still unknown ligands. Interest in KIR genotyping is increasing because of the importance of these receptors for identifying the best possible donor in...

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Detalles Bibliográficos
Autores principales: Closa, Laia, Vidal, Francisco, Herrero, Maria J., Caro, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305729/
https://www.ncbi.nlm.nih.gov/pubmed/30619344
http://dx.doi.org/10.3389/fimmu.2018.02991