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Single and Repeated Administration of Methylphenidate Modulates Synaptic Plasticity in Opposite Directions via Insertion of AMPA Receptors in Rat Hippocampal Neurons

Methylphenidate (MPH) is widely used in the treatment of Attention Deficit Hyperactivity Disorder. Several lines of evidence support that MPH can modulate learning and memory processes in different ways including improvement and impairment of test performances. A relevant factor in the efficacy of t...

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Detalles Bibliográficos
Autores principales: Carvallo, Claudia, Contreras, Darwin, Ugarte, Gonzalo, Delgado, Ricardo, Pancetti, Floria, Rozas, Carlos, Piña, Ricardo, Constandil, Luis, Zeise, Marc L., Morales, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305740/
https://www.ncbi.nlm.nih.gov/pubmed/30618772
http://dx.doi.org/10.3389/fphar.2018.01485