Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells

Adeno-associated virus (AAV) vectors are currently among the most commonly applied for in vivo gene therapy approaches. The evaluation of vectors during clinical development requires the production of considerable amounts of highly pure and potent vectors. Here, we set up a scalable process for AAV...

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Detalles Bibliográficos
Autores principales: Blessing, Daniel, Vachey, Gabriel, Pythoud, Catherine, Rey, Maria, Padrun, Vivianne, Wurm, Florian M., Schneider, Bernard L., Déglon, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305802/
https://www.ncbi.nlm.nih.gov/pubmed/30591923
http://dx.doi.org/10.1016/j.omtm.2018.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305802/
https://www.ncbi.nlm.nih.gov/pubmed/30591923
http://dx.doi.org/10.1016/j.omtm.2018.11.004

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