Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis()

Bone metastasis from breast and prostate carcinomas is facilitated by activation of bone-resorbing osteoclasts. Using proteomics approaches, we have identified peroxiredoxin-4 (PRDX4) as a cancer-secreted mediator of osteoclastogenesis. We now report characterization of L-plastin in the conditioned...

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Detalles Bibliográficos
Autores principales: Tiedemann, Kerstin, Sadvakassova, Gulzhakhan, Mikolajewicz, Nicholas, Juhas, Michal, Sabirova, Zarina, Tabariès, Sébastien, Gettemans, Jan, Siegel, Peter M., Komarova, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305809/
https://www.ncbi.nlm.nih.gov/pubmed/30583289
http://dx.doi.org/10.1016/j.tranon.2018.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305809/
https://www.ncbi.nlm.nih.gov/pubmed/30583289
http://dx.doi.org/10.1016/j.tranon.2018.11.014

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