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Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis()
Bone metastasis from breast and prostate carcinomas is facilitated by activation of bone-resorbing osteoclasts. Using proteomics approaches, we have identified peroxiredoxin-4 (PRDX4) as a cancer-secreted mediator of osteoclastogenesis. We now report characterization of L-plastin in the conditioned...
Autores principales: | Tiedemann, Kerstin, Sadvakassova, Gulzhakhan, Mikolajewicz, Nicholas, Juhas, Michal, Sabirova, Zarina, Tabariès, Sébastien, Gettemans, Jan, Siegel, Peter M., Komarova, Svetlana V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305809/ https://www.ncbi.nlm.nih.gov/pubmed/30583289 http://dx.doi.org/10.1016/j.tranon.2018.11.014 |
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