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Design and Development of Modified mRNA Encoding Core Antigen of Hepatitis C Virus: a Possible Application in Vaccine Production

BACKGROUND: Hepatitis C virus (HCV) is a blood-borne pathogen, resulting in liver cirrhosis and liver cancer. Despite of many efforts in development of treatments for HCV, no vaccine has been licensed yet. The purpose of this study was to design and prepare a specific mRNA, without 5’ cap and poly (...

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Detalles Bibliográficos
Autores principales: Sharifnia, Zarin, Bandehpour, Mojgan, Kazemi, Bahram, Zarghami, Nosratollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305823/
https://www.ncbi.nlm.nih.gov/pubmed/30056690
http://dx.doi.org/10.29252/.23.1.57