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PIK3CA Mutation Analysis in Iranian Patients with Gastric Cancer

BACKGROUND: Aberrant activation of phosphatidylinositol-3 kinases (PI3K)/AKT/mTOR (mammalian target of rapamycin) pathway is a critical event during gastric cancer progression. Selective function of AKT inhibitor AZD5363 in PI3KCA mutant gastric cancer necessitates the assessment of PI3KCA mutations...

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Detalles Bibliográficos
Autores principales: Iranpour, Mostafa, Nourian, Mahyar, Saffari, Sana, Samizadeh, Esmaeil, Mirghafori, Mahdieh, Iravani, Shahrokh, Ghafouri-Fard, Soudeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305827/
https://www.ncbi.nlm.nih.gov/pubmed/29704890
http://dx.doi.org/10.29252/.23.1.87