Cargando…

PIK3CA Mutation Analysis in Iranian Patients with Gastric Cancer

BACKGROUND: Aberrant activation of phosphatidylinositol-3 kinases (PI3K)/AKT/mTOR (mammalian target of rapamycin) pathway is a critical event during gastric cancer progression. Selective function of AKT inhibitor AZD5363 in PI3KCA mutant gastric cancer necessitates the assessment of PI3KCA mutations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iranpour, Mostafa, Nourian, Mahyar, Saffari, Sana, Samizadeh, Esmaeil, Mirghafori, Mahdieh, Iravani, Shahrokh, Ghafouri-Fard, Soudeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305827/ https://www.ncbi.nlm.nih.gov/pubmed/29704890 http://dx.doi.org/10.29252/.23.1.87

Ejemplares similares

Mutations of PIK3CA in gastric adenocarcinoma
por: Li, Vivian Sze Wing, et al.
Publicado: (2005)

A comprehensive overview of identified mutations in SARS CoV-2 spike glycoprotein among Iranian patients
por: Eslami, Solat, et al.
Publicado: (2022)

Mutation and genomic amplification of the PIK3CA proto-oncogene in pituitary adenomas
por: Murat, C.B., et al.
Publicado: (2012)

Expression Study and Clinical Correlations of MYC and CCAT2 in Breast Cancer Patients
por: Sarrafzadeh, Shaghayegh, et al.
Publicado: (2017)

ANRIL Genetic Variants in Iranian Breast Cancer Patients
por: Khorshidi, Hamid Reza, et al.
Publicado: (2017)

A Novel Splice Site Mutation in HPS1 Gene is Associated with Hermansky-Pudlak Syndrome-1 (HPS1) in an Iranian Family
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2016)

Association analysis between genomic variants within advanced glycation end product specific receptor (AGER) gene and risk of breast cancer in Iranian women
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2019)

Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab
por: Cizkova, M, et al.
Publicado: (2013)

Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19
por: Saleh Gargari, Soraya, et al.
Publicado: (2022)

Genetic Analysis of Iranian Patients with Familial Hypercholesterolemia
por: Ekrami, Mahdis, et al.
Publicado: (2018)

Prevalence and prognostic role of PIK3CA E545K mutation in Iranian colorectal cancer patients
por: Ranjbar, Reza, et al.
Publicado: (2019)

Mutations in PIK3CA are infrequent in neuroblastoma
por: Dam, Vincent, et al.
Publicado: (2006)

PIK3CA-mutations in breast cancer
por: Reinhardt, Kristin, et al.
Publicado: (2022)

PIK3CA mutation correlates with mTOR pathway expression but not clinical and pathological features in Fibfibroipose vascular anomaly (FAVA)
por: Hori, Yumiko, et al.
Publicado: (2022)

Clinicopathological Significance of Elevated PIK3CA Expression in Gastric Cancer
por: Jang, Si-Hyong, et al.
Publicado: (2016)

Abnormal Transcript Levels of Cytokines Among Iranian COVID-19 Patients
por: Samsami, Majid, et al.
Publicado: (2021)

Carcinogenesis of PIK3CA
por: German, Sidra, et al.
Publicado: (2013)

A Novel Missense Mutation in CLCN1 Gene in a Family with Autosomal Recessive Congenital Myotonia
por: Miryounesi, Mohammad, et al.
Publicado: (2016)

PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer
por: Kim, Ji-Won, et al.
Publicado: (2017)

Mutation of the PIK3CA oncogene in human cancers
por: Karakas, B, et al.
Publicado: (2006)

Initiating breast cancer by PIK3CA mutation
por: Miller, Todd W
Publicado: (2012)

PIK3CA Mutations in Hepatocellular Carcinoma in Korea
por: Kim, Heesue, et al.
Publicado: (2013)

PIK3CA Mutational Analysis of Parathyroid Adenomas
por: Riccardi, Aaliyah, et al.
Publicado: (2020)

Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers
por: Coussy, F., et al.
Publicado: (2020)

KRAS , NRAS , BRAF, and PIK3CA mutation rates, clinicopathological association, and their prognostic value in Iranian colorectal cancer patients
por: Mirzapoor Abbasabadi, Zohreh, et al.
Publicado: (2023)

Impact of ATM and SLC22A1 Polymorphisms on Therapeutic Response to Metformin in Iranian Diabetic Patients
por: Shokri, Fazlollah, et al.
Publicado: (2016)

Long Non Coding RNA Expression Intersecting Cancer and Spermatogenesis: A Systematic Review
por: Dianatpour, Ali, et al.
Publicado: (2017)

The Role of Long Non Coding RNAs in the Repair of DNA Double Strand Breaks
por: Dianatpour, Ali, et al.
Publicado: (2017)

The importance of miRNA-630 in human diseases with an especial focus on cancers
por: Kadkhoda, Sepideh, et al.
Publicado: (2022)

Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequencing technology and literature review
por: Harada, Kazuto, et al.
Publicado: (2016)

Epstein–Barr virus-associated gastric cancer reveals intratumoral heterogeneity of PIK3CA mutations
por: Böger, C., et al.
Publicado: (2017)

PIK3CA in Colorectal Cancer
por: Cathomas, Gieri
Publicado: (2014)

Autosomal Recessive Nonsyndromic Hearing Loss: A Case Report with a Mutation in TRIOBP Gene
por: Fardaei, Majid, et al.
Publicado: (2015)

Expression of PIK3CA, PTEN mRNA and PIK3CA mutations in primary breast cancer: association with lymph node metastases
por: Palimaru, Irina, et al.
Publicado: (2013)

A Mosaic PIK3CA Mutation in a Moroccan Female: Exploring the Diagnostic Challenges of PIK3CA-Related Overgrowth Spectrum
por: Ahakoud, Mohamed, et al.
Publicado: (2023)

EGFR, PIK3CA, KRAS and BRAF mutations in meningiomas
por: BUJKO, MATEUSZ, et al.
Publicado: (2014)

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes
por: Janku, Filip, et al.
Publicado: (2012)

Cancer-Associated PIK3CA Mutations in Overgrowth Disorders
por: Madsen, Ralitsa R., et al.
Publicado: (2018)

PIK3CA mutation and colorectal cancer precision medicine
por: Hamada, Tsuyoshi, et al.
Publicado: (2017)

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
por: Chen, Li, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_lj3ost9jqnh8i4a4jn2i6lua3u