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The impact of xanthine oxidase (XO) on hemolytic diseases

Hemolytic diseases are associated with elevated levels of circulating free heme that can mediate endothelial dysfunction directly via redox reactions with biomolecules or indirectly by upregulating enzymatic sources of reactive species. A key enzymatic source of these reactive species is the purine...

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Detalles Bibliográficos
Autores principales: Schmidt, Heidi M., Kelley, Eric E., Straub, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305892/
https://www.ncbi.nlm.nih.gov/pubmed/30580157
http://dx.doi.org/10.1016/j.redox.2018.101072