A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer’s Disease

Studies of Alzheimer’s disease risk-weighted polygenic risk scores (PRSs) for cognitive performance have reported inconsistent associations. This inconsistency is particularly evident when PRSs are assessed independent of APOE genotype. As such, the development and assessment of phenotype-specific w...

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Detalles Bibliográficos
Autores principales: Porter, Tenielle, Burnham, Samantha C., Savage, Greg, Lim, Yen Ying, Maruff, Paul, Milicic, Lidija, Peretti, Madeline, Ames, David, Masters, Colin L., Martins, Ralph N., Rainey-Smith, Stephanie, Rowe, Christopher C., Salvado, Olivier, Taddei, Kevin, Groth, David, Verdile, Giuseppe, Villemagne, Victor L., Laws, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305908/
https://www.ncbi.nlm.nih.gov/pubmed/30620773
http://dx.doi.org/10.3389/fnagi.2018.00423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305908/
https://www.ncbi.nlm.nih.gov/pubmed/30620773
http://dx.doi.org/10.3389/fnagi.2018.00423

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