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Caralluma fimbriata extract activity involves the 5‐HT2c receptor in PWS Snord116 deletion mouse model

INTRODUCTION: In Prader–Willi syndrome (PWS), nonprotein coding small nucleolar (sno) RNAs are involved in the paternally deleted region of chromosome 15q11.2‐q13, which is believed to cause the hyperphagic phenotype of PWS. Central to this is SnoRNA116. The supplement Caralluma fimbriata extract (C...

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Detalles Bibliográficos
Autores principales: Griggs, Joanne L., Mathai, Michael L., Sinnayah, Puspha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305914/
https://www.ncbi.nlm.nih.gov/pubmed/30353709
http://dx.doi.org/10.1002/brb3.1102