Preparation and characterization of nimodipine-loaded nanostructured lipid systems for enhanced solubility and bioavailability

PURPOSE: Nimodipine (NMP) is a clinical dihydropyridine calcium antagonist. However, the clinical application of NMP is limited by poor water solubility and low oral bioavailability. To overcome these drawbacks, this study designed optimal NMP-incorporated nanostructured lipid carriers (NLCs). METHO...

Descripción completa

Detalles Bibliográficos
Autores principales: Teng, Zaijin, Yu, Miao, Ding, Yang, Zhang, Huaqing, Shen, Yan, Jiang, Menglao, Liu, Peixin, Opoku-Damoah, Yaw, Webster, Thomas J, Zhou, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306054/
https://www.ncbi.nlm.nih.gov/pubmed/30613141
http://dx.doi.org/10.2147/IJN.S186899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306054/
https://www.ncbi.nlm.nih.gov/pubmed/30613141
http://dx.doi.org/10.2147/IJN.S186899

Ejemplares similares