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Preparation and characterization of nimodipine-loaded nanostructured lipid systems for enhanced solubility and bioavailability

PURPOSE: Nimodipine (NMP) is a clinical dihydropyridine calcium antagonist. However, the clinical application of NMP is limited by poor water solubility and low oral bioavailability. To overcome these drawbacks, this study designed optimal NMP-incorporated nanostructured lipid carriers (NLCs). METHO...

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Detalles Bibliográficos
Autores principales:	Teng, Zaijin, Yu, Miao, Ding, Yang, Zhang, Huaqing, Shen, Yan, Jiang, Menglao, Liu, Peixin, Opoku-Damoah, Yaw, Webster, Thomas J, Zhou, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306054/ https://www.ncbi.nlm.nih.gov/pubmed/30613141 http://dx.doi.org/10.2147/IJN.S186899

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