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In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model

PURPOSE: PB is one of the most severe complications of late stage prostate cancer and negatively impacts patient quality of life. A major challenge for the treatment of cancer bone metastasis is the management of efficient drug delivery to metastatic bone lesion. We aimed to explore the use of aptam...

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Detalles Bibliográficos
Autores principales: Chen, Lingxiao, He, Wei, Jiang, Huichuan, Wu, Longxiang, Xiong, Wei, Li, Bolun, Zhou, Zhihua, Qian, Yuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306056/
https://www.ncbi.nlm.nih.gov/pubmed/30613143
http://dx.doi.org/10.2147/IJN.S188003