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In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model
PURPOSE: PB is one of the most severe complications of late stage prostate cancer and negatively impacts patient quality of life. A major challenge for the treatment of cancer bone metastasis is the management of efficient drug delivery to metastatic bone lesion. We aimed to explore the use of aptam...
Autores principales: | Chen, Lingxiao, He, Wei, Jiang, Huichuan, Wu, Longxiang, Xiong, Wei, Li, Bolun, Zhou, Zhihua, Qian, Yuna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306056/ https://www.ncbi.nlm.nih.gov/pubmed/30613143 http://dx.doi.org/10.2147/IJN.S188003 |
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