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Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats

BACKGROUND: Considerable evidences support the finding that the anesthesia reagent isoflurane increases neuronal cell death in young rats. Recent studies have shown that dexmedetomidine can reduce isoflurane-induced neuronal injury, but the mechanism remains unclear. We investigated whether isoflura...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Shan, Yangyang, Tang, Zhiyin, Gao, Linlin, Liu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306062/
https://www.ncbi.nlm.nih.gov/pubmed/30613136
http://dx.doi.org/10.2147/DDDT.S163197