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Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats
BACKGROUND: Considerable evidences support the finding that the anesthesia reagent isoflurane increases neuronal cell death in young rats. Recent studies have shown that dexmedetomidine can reduce isoflurane-induced neuronal injury, but the mechanism remains unclear. We investigated whether isoflura...
Autores principales: | Wang, Xue, Shan, Yangyang, Tang, Zhiyin, Gao, Linlin, Liu, Hongtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306062/ https://www.ncbi.nlm.nih.gov/pubmed/30613136 http://dx.doi.org/10.2147/DDDT.S163197 |
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