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Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia
INTRODUCTION: Classic ataxia telangiectasia (A-T) is an autosomal recessive disease characterized by early onset ataxia, immune deficiency, sino-pulmonary disease, lymphoid/solid malignancies and telangiectasias. Prior studies have suggested that chronic inflammation and premature aging may contribu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306200/ https://www.ncbi.nlm.nih.gov/pubmed/30586396 http://dx.doi.org/10.1371/journal.pone.0209496 |