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Clonal analysis of HIV-1 genotype and function associated with virologic failure in treatment-experienced persons receiving maraviroc: Results from the MOTIVATE phase 3 randomized, placebo-controlled trials

Detailed clonal phenotypic/genotypic analyses explored viral-escape mechanisms during maraviroc-based therapy in highly treatment-experienced participants from the MOTIVATE trials. To allow real-time assessment of samples while maintaining a blind trial, the first 267 enrolled participants were sele...

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Detalles Bibliográficos
Autores principales: Lewis, Marilyn, Mori, Julie, Toma, Jonathan, Mosley, Mike, Huang, Wei, Simpson, Paul, Mansfield, Roy, Craig, Charles, van der Ryst, Elna, Robertson, David L., Whitcomb, Jeannette M., Westby, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306210/
https://www.ncbi.nlm.nih.gov/pubmed/30586365
http://dx.doi.org/10.1371/journal.pone.0204099