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Ficolin-2 binds to serotype 35B pneumococcus as it does to serotypes 11A and 31, and these serotypes cause more infections in older adults than in children

Among 98 serotypes of Streptococcus pneumoniae, only a small subset regularly causes invasive pneumococcal diseases (IPD). We previously demonstrated that serotype 11A binds to ficolin-2 and has low invasiveness in children. Epidemiologic data suggested, however, that serotype 11A IPD afflicts older...

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Detalles Bibliográficos
Autores principales: Geno, K. Aaron, Spencer, Brady L., Bae, Sejong, Nahm, Moon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306229/
https://www.ncbi.nlm.nih.gov/pubmed/30586458
http://dx.doi.org/10.1371/journal.pone.0209657