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Rapid birth-death evolution and positive selection in detoxification-type glutathione S-transferases in mammals
Glutathione S-Transferases (GSTs) are phase II detoxification enzymes that may have evolved in response to changes of environmental substrates. GST genes formed a multigene family and in mammals, there are six classes known as Alpha, Mu, Omega, Pi, Theta, and Zeta. Recent studies in phase I detoxifi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306238/ https://www.ncbi.nlm.nih.gov/pubmed/30586459 http://dx.doi.org/10.1371/journal.pone.0209336 |