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Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex
Drosophila bithorax complex (BX-C) is one of the best model systems for studying the role of boundaries (insulators) in gene regulation. Expression of three homeotic genes, Ubx, abd-A, and Abd-B, is orchestrated by nine parasegment-specific regulatory domains. These domains are flanked by boundary e...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306242/ https://www.ncbi.nlm.nih.gov/pubmed/30540750 http://dx.doi.org/10.1371/journal.pgen.1007702 |