Tumor-secreted factors induce IL-1β maturation via the glucose-mediated synergistic axis of mTOR and NF-κB pathways in mouse macrophages

Macrophages are one of the major cell types that produce IL-1β. IL-1β maturation occurs via inflammasome activation, and mature IL-1β is then released from the cell. Secreted IL-1β mediates inflammatory reactions in various pathological environments, such as those in infectious, autoimmune, and canc...

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Detalles Bibliográficos
Autores principales: Woo, Yunseo, Kim, Hyeran, Kim, Keun-Cheol, Han, Jeong A., Jung, Yu-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306269/
https://www.ncbi.nlm.nih.gov/pubmed/30586442
http://dx.doi.org/10.1371/journal.pone.0209653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306269/
https://www.ncbi.nlm.nih.gov/pubmed/30586442
http://dx.doi.org/10.1371/journal.pone.0209653

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