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P38 MAPK inhibition prevents polybrene-induced senescence of human mesenchymal stem cells during viral transduction

The unique capacity of mesenchymal stem cells (MSCs) to migrate to the sites of damage, following intravenous transplantation, along with their proliferation and differentiation abilities make them promising candidates for MSC-based gene therapy. This therapeutic approach requires high efficacy deli...

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Detalles Bibliográficos
Autores principales: Griukova, Anastasiia, Deryabin, Pavel, Sirotkina, Maria, Shatrova, Alla, Nikolsky, Nikolay, Borodkina, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306270/
https://www.ncbi.nlm.nih.gov/pubmed/30586456
http://dx.doi.org/10.1371/journal.pone.0209606