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The streptozotocin-high fat diet induced diabetic mouse model exhibits severe skin damage and alterations in local lipid mediators

BACKGROUND: Type 2 diabetes (T2D) can go undiagnosed for years, leading to a stage where produces complications such as delayed skin wound healing. Animal models have been developed in the last decades to study the pathological progression in this disease. Streptozotocin (STZ), that has a selective...

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Detalles Bibliográficos
Autores principales: Leguina-Ruzzi, Alberto, Ortiz, Rina, Velarde, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306302/
https://www.ncbi.nlm.nih.gov/pubmed/30580797
http://dx.doi.org/10.1016/j.bj.2018.08.005